A focus on enzymes paves way to petroleum-free fuels

Researchers at Berkeley Lab have developed an innovative experimental system to unravel the intricacies of cellulose breakdown by enzymes. Cellulose, composed of glucose molecules held together by covalent bonds, forms complex fibrils stabilized by hydrogen bonds. These bonds hinder enzyme access to covalent bonds, slowing cellulose-chopping.

To gain insight into this mechanism, Berkeley Lab scientists designed a device containing cellulose from green algae and enzymes derived from fungi. This setup facilitates real-time observation of structural changes in cellulose during enzymatic reactions.